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UNESP · São Paulo · Brazil
Nanobionics
Research Group
We investigate quantum electrodynamics at molecular interfaces — uncovering how E = hν governs electron dynamics in electrolytic environments, and translating those insights into high-sensitivity platforms for disease diagnosis and drug discovery.
Think about…
The most beautiful thing we can experience is the mysterious. It is the source of all true art and science.
You cannot teach a man anything; you can only find it within yourself.
The future is uncertain… but this uncertainty is at the very heart of human creativity.
An absolute can only be given in an intuition, while all the rest has to do with analysis.
An experiment is a question which science poses to Nature, and a measurement is the recording of Nature's answer.
Our Mission
Nanobionics develops a unified quantum-rate (QR) theory of charge transfer and transport in electrolytic environments, grounded in low-energy quantum electrodynamics. The central experimental observable is the quantum capacitance Cq — directly proportional to the electronic density of states of a molecular or nanoscale interface — which encodes both equilibrium thermodynamics and kinetic information in a single impedance measurement. We apply this framework to two interconnected goals: molecular diagnostics, where Cq-based label-free assays detect disease biomarkers at femtomolar to attomolar concentrations in complex biofluids; and drug discovery, where the same signal delivers binding affinity constants Ka and Gibbs free energies with internal thermodynamic validation unavailable to surface plasmon resonance or ITC.
Research Areas
Low-Energy Quantum Electrodynamics
Cq links the conductance quantum G0 to the electron transfer rate through ν = e²/hCq, unifying solid-state electronics and electrochemistry under a single Planck–Einstein framework. Demonstrated spectroscopically on graphene and CdTe quantum dots at room temperature.
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Quantum in 'Wet' Environments
Ionic screening drives Ce toward equivalence with Cq — the isoscopic condition — locking Rq ≈ 12.9 kΩ and sustaining coherent electron dynamics at room temperature. Verified in microbial respiration and redox monolayer junctions across multiple solvents.
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Quantum Electrochemistry
Marcus theory and the Levich–Dogonadze–Kuznetsov model emerge as limiting cases of QR theory. Parameter-free predictions of the electron-transfer rate from equilibrium Cq alone — verified against independently measured Laviron rate constants at zero free parameters.
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Quantum Sensing & Molecular Diagnostics
Molecular recognition at redox-SAM, graphene, or quantum-dot interfaces shifts Cq through the density of states. A single EIS titration yields femtomolar-to-attomolar detection of disease biomarkers and simultaneously delivers Ka with thermodynamic validation via Rq invariance.
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Address
Institute of Chemistry · UNESP
R. Prof. Francisco Degni, 55 – Quitandinha
Araraquara · São Paulo · Brazil · 14800-060